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ea0022p145 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Ligands of receptor for advanced glycation end-products in stable coronary artery disease: their potential contribution to atherogenesis exceeds beyond diabetes mellitus

Kuliczkowska-Plaksej Justyna , Bednorz Wlodzimierz , Bednarek-Tupikowska Grazyna , Plaksej Rafal , Derzhko Roksolana , Spring Adam , Milewicz Andrzej

Receptor for advanced glycation end-products (RAGE) signalling, crucial for diabetic macroangiopathy, is also highly suspected to be involved in atherogenesis in the setting of preserved glucose metabolism.Aim: To determine the relationships between peripheral blood concentrations of RAGE agonists, namely amfoterin (HMBG1) and carboxy-methylo-lisine (CML) as well as RAGE inhibitor Endogenously Secretory RAGE (esRAGE), and the severity of atherosclerosis ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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